2. Belar A, Arantzamendi M, Payne S, Preston
N, Rijpstra M, Hasselaar J, et al. How to
measure the effects and potential adverse
events of palliative sedation? An integrative
review. Palliat Med. 2021;35(2):295-314. doi:
10.1177/0269216320974264
3. Cherny NI, Radbruch L and Board of the
European Association for Palliative C.
European Association for Palliative Care
(EAPC) recommended framework for the use
of sedation in palliative care. Palliat Med
2009; 23: 581-593. doi:
10.1177/0269216309107024
4. Juth N, Lindblad A, Lynöe N, Sjöstrand M,
Helgesson G. European Association for
Palliative Care (EAPC) framework for
palliative sedation: an ethical discussion.
BMC Palliat Care. 2010;9:20. doi:
10.1186/1472-684X-9-20
5. Mercadante S, Porzio G, Valle A, Aielli F,
Casuc cio A, Home Care-Italy Group. Palliative
sedation in patients with advanced cancer
followed at home: a prospective study. J Pain
Symptom Manage. 2014;47(5):860-6. doi:
10.1016/j.jpainsymman.2013.06.019
6. Pype P, Teuwen I, Mertens F, Sercu M, De
Sutter A. Suboptimal palliative sedation in
primary care: an exploration. Acta Clin Belg.
2018;73(1):21-28. doi:
10.1080/17843286.2017.1331783
7. Caraceni A, Speranza R, Spoldi E, Ambroset
CS, Canestrari S, Marinari M, et al. Palliative
Sedation in Terminal Cancer Patients
Admitted to Hospice or Home Care
Programs: Does the Setting Matter? Results
From a National Multicenter Observational
Study. J Pain Symptom Manage.
2018;56(1):33-43. doi:
10.1016/j.jpainsymman.2018.03.008
8. van Deijck RH, Hasselaar JG, Verhagen SC,
Vissers KC, Koopmans RT. Patient-Related
Determinants of the Administration of
Continuous Palliative Sedation in Hospices
and Palliative Care Units: A Prospective,
Multicenter, Observational Study. J Pain
Symptom Manage. 2016;51(5):882-9. doi:
10.1016/j.jpainsymman
9. van Deijck RH, Hasselaar JG, Verhagen SC,
Vissers KC, Koopmans RT. Level of
Discomfort Decreases After the
Administration of Continuous Palliative
Sedation: A Prospective Multicenter Study in
Hospices and Palliative Care Units. J Pain
Symptom Manage. 2016;52(3):361-9. doi:
10.1016/j.jpainsymman.2016.05.008
10. Monreal-Carrillo E, Allende-Pérez S, Hui
D, García-Salamanca MF, Bruera E,
Verástegui E. Bispectral Index monitoring in
cancer patients undergoing palliative
sedation: a preliminary report. Support Care
Cancer. 2017;25(10):3143-3149. doi:
10.1007/s00520-017-3722-8
11. Imai K, Morita T, Yokomichi N, Mori M,
Naito AS, Tsukuura H, et al. Efficacy of two
types of palliative sedation therapy defined
using intervention protocols: proportional vs.
deep sedation. Support Care Cancer.
2018;26(6):1763-1771. doi: 10.1007/s00520-
017-4011-2
12. Claessens P, Menten J, Schotsmans P,
Broeckaert B; Palsed Consortium. Palliative
sedation, not slow euthanasia: a prospective,
longitudinal study of sedation in Flemish
palliative care units. J Pain Symptom
Manage. 2011;41(1):14-24. doi:
10.1016/j.jpainsymman.2010.04.019
13. Broeckaert B, Nunez-Olarte JM. Sedation
in palliative care: facts and concepts. In: Ten
19